SCHEMBL8716229

SCHEMBL8716229

CC(Cc1ccccc1Cl)C(N)C(O)c1ccccc1OCc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 2/20 0.43
FABP5 Q01469 2/20 0.43
SGMS2 Q8NHU3 2/20 0.42
HPGD P15428 3/20 0.39
RXRA P19793 1/20 0.39
RXRB P28702 1/20 0.39
SLC1A5 Q15758 2/20 0.38
PTGER1 P34995 1/20 0.38
PTGER4 P35408 1/20 0.38
PTGER3 P43115 1/20 0.38
PTGER2 P43116 1/20 0.38
HTR1A P08908 1/20 0.38
DRD2 P14416 1/20 0.38
MME P08473 1/20 0.38
ACE P12821 1/20 0.38
CPA1 P15085 1/20 0.38
ACE2 Q9BYF1 1/20 0.38
LIPE Q05469 1/20 0.37
LMNA P02545 1/20 0.37
CFD P00746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8716228 1.00 FABP4 (0.43) FABP4FABP5SGMS2HPGDRXRA
SCHEMBL8713617 0.87 ABCB1 (0.43) SGMS2RXRAHTR1ADRD2MME
SCHEMBL8713614 0.87 ABCB1 (0.43) SGMS2RXRAHTR1ADRD2MME
SCHEMBL8713629 0.87 SGMS2 (0.43) SGMS2RXRARXRBSLC1A5PTGER1
SCHEMBL8713626 0.87 SGMS2 (0.43) SGMS2RXRARXRBSLC1A5PTGER1
SCHEMBL8713787 0.86 SLC6A2 (0.42) FABP4FABP5
SCHEMBL8713784 0.86 SLC6A2 (0.42) FABP4FABP5
SCHEMBL8713904 0.81 SLC6A2 (0.45) LMNA
SCHEMBL8713907 0.81 SLC6A2 (0.45) LMNA
SCHEMBL8716922 0.80 CFD (0.47) HPGDPTGER1PTGER4PTGER3PTGER2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5811293-A CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1998-09-22 US disclosed