Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SCN4A | P35499 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | SLC1A5 | Q15758 | 2/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713629 | 1.00 | SGMS2 (0.43) | SGMS2TDP1MAPTMAPK1L3MBTL1 | |
| SCHEMBL8713614 | 0.88 | ABCB1 (0.43) | SGMS2L3MBTL1RXRAHTR1ADRD2 | |
| SCHEMBL8713617 | 0.88 | ABCB1 (0.43) | SGMS2L3MBTL1RXRAHTR1ADRD2 | |
| SCHEMBL8716228 | 0.87 | FABP4 (0.43) | SGMS2RXRARXRBHTR1ADRD2 | |
| SCHEMBL8716229 | 0.87 | FABP4 (0.43) | SGMS2RXRARXRBHTR1ADRD2 | |
| SCHEMBL8714177 | 0.85 | KMT2A (0.39) | MAPK1ADRA1A | |
| SCHEMBL8714178 | 0.85 | KMT2A (0.39) | MAPK1ADRA1A | |
| SCHEMBL8714092 | 0.82 | TAAR1 (0.38) | ALDH1A1LMNAGAAKDM4E | |
| SCHEMBL8714091 | 0.82 | TAAR1 (0.38) | ALDH1A1LMNAGAAKDM4E | |
| SCHEMBL8716922 | 0.81 | CFD (0.47) | TDP1MAPTMAPK1L3MBTL1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |