Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.41 |
| ▸ | RXRB | P28702 | 3/20 | 0.41 |
| ▸ | RXRG | P48443 | 2/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | FABP4 | P15090 | 3/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.38 |
| ▸ | SLC1A5 | Q15758 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713631 | 0.88 | RXRA (0.42) | RXRARXRBRXRGSGMS2SLC1A5 | |
| SCHEMBL8713622 | 0.88 | ABCB1 (0.42) | RXRARXRBRXRGSGMS2HTR1A | |
| SCHEMBL8713790 | 0.85 | NR3C1 (0.47) | MEN1KMT2AMAPT | |
| SCHEMBL8713910 | 0.82 | SLC6A2 (0.41) | NFKB1SMN1; SMN2HTT | |
| SCHEMBL8716927 | 0.80 | HTR1A (0.44) | HPGDSLC1A5HTR1ADRD2LIPE | |
| SCHEMBL8716208 | 0.78 | SLC6A2 (0.38) | NFKB1HTT | |
| SCHEMBL8718570 | 0.78 | SLC6A2 (0.38) | NFKB1TDP1 | |
| SCHEMBL8714242 | 0.78 | SLC6A2 (0.38) | MEN1NFKB1KMT2ASMN1; SMN2HTT | |
| SCHEMBL8718108 | 0.78 | ABCB1 (0.46) | RXRARXRBRXRGMEN1NPC1 | |
| SCHEMBL8719259 | 0.78 | NR3C1 (0.39) | MEN1NPC1RAB9AKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |