Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 3/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713790 | 0.90 | NR3C1 (0.47) | NR3C1NR3C2IDO1TAAR1PGR | |
| SCHEMBL8716180 | 0.90 | IDO1 (0.41) | NR3C1NR3C2IDO1TAAR1LMNA | |
| SCHEMBL8713610 | 0.90 | LMNA (0.43) | NR3C1NR3C2IDO1LMNAPGR | |
| SCHEMBL8713910 | 0.87 | SLC6A2 (0.41) | NR3C1NR3C2IDO1TAAR1LMNA | |
| SCHEMBL8720320 | 0.86 | NR3C1 (0.41) | NR3C1NR3C2IDO1TAAR1LMNA | |
| SCHEMBL8716700 | 0.86 | MPO (0.40) | NR3C1NR3C2IDO1TAAR1LMNA | |
| SCHEMBL8716634 | 0.86 | NR3C1 (0.38) | NR3C1NR3C2IDO1TAAR1LMNA | |
| SCHEMBL8717467 | 0.82 | MEN1 (0.48) | IDO1TAAR1LMNASMN1; SMN2MAPT | |
| SCHEMBL8719246 | 0.82 | ATM (0.40) | NR3C1NR3C2SMN1; SMN2CASRALDH1A1 | |
| SCHEMBL8714402 | 0.82 | KCNH2 (0.38) | NR3C1NR3C2IDO1TAAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |