Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7219609 | 0.76 | CPB2 (0.35) | CPB2GSRRNPEP | |
| SCHEMBL8710584 | 0.74 | CDK5 (0.40) | — | |
| SCHEMBL7226858 | 0.72 | FOLH1 (0.47) | CPB2GSRRNPEP | |
| SCHEMBL7226860 | 0.72 | FOLH1 (0.47) | CPB2GSRRNPEP | |
| SCHEMBL7909780 | 0.71 | NOS2 (0.42) | GSR | |
| SCHEMBL7909776 | 0.71 | NOS2 (0.42) | GSR | |
| SCHEMBL7226730 | 0.68 | CPB2 (0.38) | CPB2GSRRNPEP | |
| SCHEMBL30923406 | 0.66 | GSR (0.47) | CPB2GSRRNPEP | |
| SCHEMBL6276609 | 0.65 | CPB2 (0.41) | CPB2GSRRNPEP | |
| SCHEMBL7218411 | 0.65 | CPB2 (0.36) | CPB2GSRRNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885188-A1 | HYDROXYAMIDINO DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | G.D. SEARLE & CO. (US) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997032844-A1 | HYDROXYAMIDINO DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | G.D. SEARLE & CO. (US) | 1997-09-12 | — | — | WO | disclosed |