Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 11/20 | 0.51 |
| ▸ | MEN1 | O00255 | 10/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8710997 | 0.82 | MEN1 (0.54) | KMT2AMEN1GAAALOX15RECQL | |
| SCHEMBL1685398 | 0.79 | KMT2A (0.56) | KMT2AMEN1GAANPC1RAB9A | |
| SCHEMBL8711085 | 0.77 | KMT2A (0.51) | KMT2AMEN1GAANPC1RAB9A | |
| SCHEMBL11072116 | 0.77 | KMT2A (0.49) | KMT2AMEN1GAANPC1RAB9A | |
| SCHEMBL11065342 | 0.77 | HTT (0.53) | KMT2AMEN1GAANPC1RAB9A | |
| SCHEMBL11067046 | 0.76 | KMT2A (0.56) | KMT2AMEN1GAANPC1RAB9A | |
| SCHEMBL8661222 | 0.73 | MEN1 (0.48) | KMT2AMEN1GAAALOX15RECQL | |
| SCHEMBL11563108 | 0.70 | HPGD (0.54) | KMT2AMEN1GAAALOX15RECQL | |
| SCHEMBL5955047 | 0.69 | KMT2A (0.56) | KMT2AMEN1GAANPC1RAB9A | |
| SCHEMBL5955275 | 0.69 | KMT2A (0.56) | KMT2AMEN1GAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5821372-A | USEFUL FOR INCREASING BLOOD SERUM HIGH DENSITY LIPOPROTEIN LEVELS(HDL) | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-10-13 | — | — | US | claimed |
| US-5821372-A | USEFUL FOR INCREASING BLOOD SERUM HIGH DENSITY LIPOPROTEIN LEVELS(HDL) | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-10-13 | — | — | US | disclosed |
| US-5554607-A | INCREASING HDL CHOLESTEROL | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-09-10 | — | — | US | disclosed |