Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.40 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8661222 | 0.89 | MEN1 (0.48) | MEN1KMT2AGAAALOX15POLB | |
| SCHEMBL8716657 | 0.82 | KMT2A (0.51) | MEN1KMT2AGAAALOX15RECQL | |
| SCHEMBL9013865 | 0.81 | POLB (0.46) | MEN1KMT2AGAAPOLBHCRTR1 | |
| SCHEMBL8664639 | 0.79 | MEN1 (0.52) | MEN1KMT2AGAAPOLBP2RX7 | |
| SCHEMBL8475120 | 0.74 | MEN1 (0.52) | MEN1KMT2AGAAPOLBHCRTR1 | |
| SCHEMBL8713633 | 0.73 | PKM (0.55) | MEN1KMT2AGAAPOLBMAPT | |
| SCHEMBL8710977 | 0.73 | KMT2A (0.44) | MEN1KMT2APOLBP2RX7 | |
| SCHEMBL8661948 | 0.73 | MEN1 (0.55) | MEN1KMT2APOLBP2RX7 | |
| SCHEMBL8663001 | 0.73 | MEN1 (0.58) | MEN1KMT2AGAAPOLBP2RX7 | |
| SCHEMBL10785120 | 0.73 | POLB (0.60) | MEN1KMT2AGAAPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5821372-A | USEFUL FOR INCREASING BLOOD SERUM HIGH DENSITY LIPOPROTEIN LEVELS(HDL) | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-10-13 | — | — | US | claimed |
| US-5554607-A | INCREASING HDL CHOLESTEROL | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-09-10 | — | — | US | claimed |
| US-5821372-A | USEFUL FOR INCREASING BLOOD SERUM HIGH DENSITY LIPOPROTEIN LEVELS(HDL) | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-10-13 | — | — | US | disclosed |
| US-5554607-A | INCREASING HDL CHOLESTEROL | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-09-10 | — | — | US | disclosed |