Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 15/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716779 | 0.78 | ATP4A (0.43) | — | |
| SCHEMBL4443997 | 0.78 | PPARG (0.55) | PPARGPPARA | |
| SCHEMBL1847381 | 0.76 | PPARG (0.42) | PPARGSIGMAR1PPARA | |
| SCHEMBL12521876 | 0.75 | PPARG (0.59) | PPARG | |
| SCHEMBL1848909 | 0.75 | PPARG (0.59) | PPARG | |
| SCHEMBL6802579 | 0.75 | SIGMAR1 (0.42) | PPARGCXCR1SIGMAR1PPARA | |
| SCHEMBL1847378 | 0.74 | PPARG (0.64) | PPARGPPARA | |
| SCHEMBL1848911 | 0.73 | PPARG (0.47) | PPARG | |
| SCHEMBL8650157 | 0.72 | FFAR1 (0.58) | PPARGPPARA | |
| SCHEMBL8719493 | 0.68 | ALDH1A1 (0.46) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756525-A | USING A THIAZOLIDINEDIONE COMPOUND | BEECHAM GROUP PLC (GB) | 1998-05-26 | — | — | US | claimed |
| US-5756525-A | USING A THIAZOLIDINEDIONE COMPOUND | BEECHAM GROUP PLC (GB) | 1998-05-26 | — | — | US | disclosed |