Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 6/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.35 |
| ▸ | NTRK3 | Q16288 | 4/20 | 0.35 |
| ▸ | NTRK2 | Q16620 | 4/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717605 | 0.81 | DPP4 (0.46) | HSD11B1DPP4DPP8DPP9DPP7 | |
| SCHEMBL8719914 | 0.75 | CHRM2 (0.40) | DPP4DPP7OPRM1 | |
| SCHEMBL8719817 | 0.74 | ADRA2A (0.42) | OPRM1 | |
| SCHEMBL6425485 | 0.72 | KCNA3 (0.44) | DPP4DPP7OPRM1 | |
| SCHEMBL8716987 | 0.71 | GRIN2B (0.43) | DPP4DPP8DPP9DPP7SLC6A2 | |
| SCHEMBL8717613 | 0.71 | DPP4 (0.35) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL8717426 | 0.71 | DPP4 (0.40) | HSD11B1DPP4DPP8DPP9DPP7 | |
| SCHEMBL8719795 | 0.70 | DPP7 (0.43) | HSD11B1DPP4DPP7OPRM1 | |
| SCHEMBL8717438 | 0.70 | DPP4 (0.48) | HSD11B1DPP4DPP8DPP7 | |
| SCHEMBL8720343 | 0.68 | DPP4 (0.45) | HSD11B1DPP4DPP8DPP7OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569802-B1 | Arylacetamides | MERCK PATENT GMBH (DE) | 1998-07-15 | — | — | EP | disclosed |
| EP-0569802-A1 | Arylacetamides | MERCK PATENT GmbH (DE) | 1993-11-18 | — | — | EP | disclosed |