Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 6/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.38 |
| ▸ | HTR2A | P28223 | 5/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.38 |
| ▸ | HTR2B | P41595 | 4/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717613 | 0.88 | DPP4 (0.35) | GRIN2BGRIN1KCNH2DPP4DPP8 | |
| SCHEMBL8717426 | 0.88 | DPP4 (0.40) | GRIN2BGRIN1KCNH2LMNAOPRK1 | |
| SCHEMBL8717605 | 0.87 | DPP4 (0.46) | KCNH2DPP4DPP8DPP9DPP7 | |
| SCHEMBL8719795 | 0.87 | DPP7 (0.43) | SIGMAR1OPRK1DPP4DPP7 | |
| SCHEMBL6425485 | 0.87 | KCNA3 (0.44) | GRIN2BGRIN1OPRK1CYP2D6DPP4 | |
| SCHEMBL8720343 | 0.85 | DPP4 (0.45) | OPRK1DPP4DPP8DPP7 | |
| SCHEMBL8717438 | 0.83 | DPP4 (0.48) | KCNH2DPP4DPP8DPP7 | |
| SCHEMBL8719950 | 0.81 | HPGD (0.40) | LMNARAB9ACYP2D6ALDH1A1 | |
| SCHEMBL8719914 | 0.72 | CHRM2 (0.40) | OPRK1TSHRDPP4KDM4EMAPT | |
| SCHEMBL8716985 | 0.71 | HSD11B1 (0.42) | SLC6A2DPP4DPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569802-B1 | Arylacetamides | MERCK PATENT GMBH (DE) | 1998-07-15 | — | — | EP | disclosed |
| EP-0569802-A1 | Arylacetamides | MERCK PATENT GmbH (DE) | 1993-11-18 | — | — | EP | disclosed |