Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.37 |
| ▸ | WDR91 | A4D1P6 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717426 | 0.87 | DPP4 (0.40) | DPP7DPP4HSD11B1OPRM1OPRD1 | |
| SCHEMBL8717613 | 0.87 | DPP4 (0.35) | DPP7DPP4 | |
| SCHEMBL8716987 | 0.87 | GRIN2B (0.43) | DPP7DPP4SIGMAR1OPRK1 | |
| SCHEMBL8717605 | 0.86 | DPP4 (0.46) | DPP7DPP4HSD11B1 | |
| SCHEMBL6425485 | 0.85 | KCNA3 (0.44) | DPP7DPP4OPRM1OPRD1OPRK1 | |
| SCHEMBL8720343 | 0.83 | DPP4 (0.45) | DPP7DPP4HSD11B1OPRM1OPRD1 | |
| SCHEMBL8717438 | 0.82 | DPP4 (0.48) | DPP7DPP4HSD11B1 | |
| SCHEMBL8719950 | 0.80 | HPGD (0.40) | OPRM1 | |
| SCHEMBL8716792 | 0.77 | ADRB2 (0.48) | DPP7DPP4ADRB2OPRM1 | |
| SCHEMBL9132027 | 0.72 | ADRA2A (0.48) | HSD11B1SIGMAR1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569802-B1 | Arylacetamides | MERCK PATENT GMBH (DE) | 1998-07-15 | — | — | EP | disclosed |
| EP-0569802-A1 | Arylacetamides | MERCK PATENT GmbH (DE) | 1993-11-18 | — | — | EP | disclosed |