Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.46 |
| ▸ | TEAD1 | P28347 | 5/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717605 | 0.85 | DPP4 (0.46) | DPP4DPP7DPP8HSD11B1KCNH2 | |
| SCHEMBL8717613 | 0.83 | DPP4 (0.35) | DPP4DPP7DPP8KCNH2 | |
| SCHEMBL8716987 | 0.83 | GRIN2B (0.43) | DPP4DPP7DPP8KCNH2 | |
| SCHEMBL8717426 | 0.83 | DPP4 (0.40) | DPP4DPP7DPP8HSD11B1KCNH2 | |
| SCHEMBL8719795 | 0.82 | DPP7 (0.43) | DPP4DPP7HSD11B1 | |
| SCHEMBL6425485 | 0.82 | KCNA3 (0.44) | DPP4DPP7 | |
| SCHEMBL8720343 | 0.80 | DPP4 (0.45) | DPP4DPP7DPP8HSD11B1 | |
| SCHEMBL8719950 | 0.77 | HPGD (0.40) | — | |
| SCHEMBL22459191 | 0.74 | — | — | |
| SCHEMBL8716985 | 0.70 | HSD11B1 (0.42) | DPP4DPP7DPP8HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569802-B1 | Arylacetamides | MERCK PATENT GMBH (DE) | 1998-07-15 | — | — | EP | disclosed |
| EP-0569802-A1 | Arylacetamides | MERCK PATENT GmbH (DE) | 1993-11-18 | — | — | EP | disclosed |