SCHEMBL871727

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8181685	0.94	METAP2 (0.37)	PDE4BL3MBTL3MBTD1L3MBTL1TP53BP1
	SCHEMBL870966	0.94	METAP2 (0.37)	PDE4BL3MBTL3MBTD1L3MBTL1TP53BP1
	SCHEMBL870965	0.94	METAP2 (0.37)	PDE4BL3MBTL3MBTD1L3MBTL1TP53BP1
	SCHEMBL3023140	0.89	PDE4B (0.47)	PDE4BDRD2DRD4DRD3AXL
	SCHEMBL870187	0.88	PDE4B (0.41)	PDE4BNPSR1TSHRCRHBPCRHR2
	SCHEMBL871025	0.88	CHKA (0.41)	AXLMERTK
	SCHEMBL870188	0.88	PDE4B (0.41)	PDE4BNPSR1TSHRCRHBPCRHR2
	SCHEMBL872430	0.88	CHKA (0.41)	AXLMERTK
	SCHEMBL870887	0.87	VCP (0.37)	DRD2DRD4DRD3NPSR1TSHR
	SCHEMBL870886	0.87	VCP (0.37)	DRD2DRD4DRD3NPSR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.