Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.31 |
| ▸ | NQO1 | P15559 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716900 | 0.84 | CA9 (0.48) | CA9MAPTLMNACA12CA1 | |
| SCHEMBL19440209 | 0.77 | MAPT (0.56) | MAPTLMNANQO1 | |
| SCHEMBL9164412 | 0.75 | MAPT (0.36) | MAPTNQO1 | |
| SCHEMBL9739745 | 0.75 | MAPT (0.40) | MAPTLMNANQO1 | |
| SCHEMBL8722679 | 0.73 | MAPT (0.35) | MAPTNQO1 | |
| SCHEMBL4326638 | 0.73 | CYP19A1 (0.41) | MAPTNQO1 | |
| SCHEMBL4465114 | 0.73 | CYP19A1 (0.41) | MAPTLMNANQO1 | |
| SCHEMBL8556354 | 0.73 | MAPT (0.35) | MAPTNQO1 | |
| SCHEMBL28902991 | 0.73 | KDM2B (0.37) | — | |
| SCHEMBL4050347 | 0.73 | CA1 (0.39) | CA9CA1NQO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763455-A | SEROTONIN RECEPTOR ANTAGONISTS | WAKE FOREST UNIVERSITY (US) | 1998-06-09 | — | — | US | disclosed |
| US-5760055-A | PSYCHOLOGICAL AND NERVOUS SYSTEM DISORDERS | WAKE FOREST UNIVERSITY (US) | 1998-06-02 | — | — | US | disclosed |