Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 12/20 | 0.62 |
| ▸ | MTNR1B | P49286 | 11/20 | 0.62 |
| ▸ | HTR6 | P50406 | 1/20 | 0.61 |
| ▸ | NQO2 | P16083 | 1/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717163 | 0.91 | MTNR1A (0.74) | MTNR1AMTNR1BHTR6NQO2HDAC3 | |
| SCHEMBL8712203 | 0.89 | MTNR1A (0.61) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL6938945 | 0.84 | MTNR1A (0.58) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL25028279 | 0.83 | HTR6 (0.67) | MTNR1AMTNR1BHTR6NQO2HDAC3 | |
| SCHEMBL8717495 | 0.82 | HTR6 (0.62) | MTNR1AMTNR1BHTR6NQO2HDAC3 | |
| SCHEMBL20307266 | 0.82 | HDAC3 (0.59) | MTNR1AMTNR1BNQO2HDAC3HDAC6 | |
| SCHEMBL31414219 | 0.80 | MTNR1A (0.58) | MTNR1AMTNR1BNQO2HDAC3HDAC6 | |
| SCHEMBL23950141 | 0.77 | MTNR1A (0.69) | MTNR1AMTNR1BNQO2HDAC3HDAC6 | |
| SCHEMBL16068348 | 0.77 | HDAC3 (0.73) | MTNR1AMTNR1BNQO2HDAC3HDAC6 | |
| SCHEMBL16068372 | 0.76 | HDAC3 (0.68) | MTNR1AMTNR1BHTR6NQO2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770610-A | ADMINISTERING R-(+)-N-(2-METHYL-2-(5-METHOXY-6-CHLOROINDOL-3-YL)ETHYL) ACETAMIDE | ELI LILLY AND COMPANY (US) | 1998-06-23 | — | — | US | disclosed |