Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 13/20 | 0.58 |
| ▸ | MTNR1B | P49286 | 12/20 | 0.58 |
| ▸ | NQO2 | P16083 | 1/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6944686 | 0.92 | MTNR1A (0.57) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL194360 | 0.90 | MTNR1A (0.73) | MTNR1AMTNR1BNQO2AKR1C3 | |
| SCHEMBL7122186 | 0.88 | MTNR1A (0.55) | MTNR1AMTNR1BNQO2AKR1C3 | |
| SCHEMBL6939654 | 0.88 | MTNR1A (0.57) | MTNR1AMTNR1BNQO2AKR1C3 | |
| SCHEMBL6944873 | 0.85 | MTNR1A (0.54) | MTNR1AMTNR1BNQO2AKR1C3 | |
| SCHEMBL8717743 | 0.84 | MTNR1A (0.62) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL6949412 | 0.81 | MTNR1A (0.49) | MTNR1AMTNR1BNQO2AKR1C3 | |
| SCHEMBL7134814 | 0.81 | MTNR1A (0.61) | MTNR1AMTNR1BNQO2AKR1C3 | |
| SCHEMBL6833442 | 0.79 | ADRB2 (0.67) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL6921381 | 0.77 | MTNR1A (0.57) | MTNR1AMTNR1BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004085395-A1 | MELATONIN DERIVATIVES AND THEIR USE FOR TREATING NEUROLOGICAL DYSFUNCTIONS | FAUST PHARMACEUTICALS (FR) | 2004-10-07 | — | — | WO | disclosed |