Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.62 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.52 |
| ▸ | NQO2 | P16083 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25028279 | 0.86 | HTR6 (0.67) | HTR6MTNR1AMTNR1BNQO2KDM4E | |
| SCHEMBL8717743 | 0.82 | MTNR1A (0.62) | HTR6MTNR1AMTNR1BNQO2HDAC3 | |
| SCHEMBL8717163 | 0.82 | MTNR1A (0.74) | HTR6MTNR1AMTNR1BNQO2KDM4E | |
| SCHEMBL6949412 | 0.82 | MTNR1A (0.49) | HTR6MTNR1AMTNR1BNQO2HDAC3 | |
| SCHEMBL24878202 | 0.77 | HTR6 (1.00) | HTR6 | |
| SCHEMBL25418921 | 0.75 | HTR6 (0.70) | HTR6MTNR1AMTNR1BNQO2HDAC3 | |
| SCHEMBL1785990 | 0.75 | BCHE (0.57) | HTR6KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL24878072 | 0.73 | HTR6 (0.57) | HTR6MTNR1AMTNR1BNQO2HDAC3 | |
| SCHEMBL9492326 | 0.72 | MTNR1A (0.67) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL6506680 | 0.72 | ADRA1A (0.57) | MTNR1AMTNR1BHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5770610-A | ADMINISTERING R-(+)-N-(2-METHYL-2-(5-METHOXY-6-CHLOROINDOL-3-YL)ETHYL) ACETAMIDE | ELI LILLY AND COMPANY (US) | 1998-06-23 | — | — | US | disclosed |