Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717783 | 0.87 | GPR84 (0.38) | CYP1A2CYP2A6NR1I2ALDH1A1HSD17B10 | |
| SCHEMBL6402798 | 0.85 | ALDH1A1 (0.35) | CYP1A2CYP2A6ALDH1A1HSD17B10HIF1A | |
| SCHEMBL8717051 | 0.84 | TLR8 (0.40) | CYP1A2ATMMAPTMEN1KMT2A | |
| SCHEMBL29497335 | 0.84 | TDP1 (0.44) | CYP1A2CYP2A6ALDH1A1HSD17B10ATM | |
| SCHEMBL2098306 | 0.84 | TDP1 (0.44) | CYP1A2CYP2A6ALDH1A1HSD17B10ATM | |
| SCHEMBL8715524 | 0.83 | TLR8 (0.41) | ALDH1A1HSD17B10KDM4EMAPTMEN1 | |
| SCHEMBL29266169 | 0.82 | THRA (0.43) | ALDH1A1HSD17B10KDM4EMAPTMEN1 | |
| SCHEMBL29266155 | 0.82 | THRA (0.43) | ALDH1A1HSD17B10KDM4EMAPTMEN1 | |
| SCHEMBL8741109 | 0.82 | THRA (0.43) | ALDH1A1HSD17B10KDM4EMAPTMEN1 | |
| SCHEMBL8718986 | 0.82 | THRA (0.43) | ALDH1A1HSD17B10KDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109906238-A | Copolymer rubber and its manufacturing method and crosslinked rubber composition | 日铁化学材料株式会社 | 2019-06-18 | — | — | CN | disclosed |
| US-RE35773-E | SILOXANE-ADDITION POLYMER COMPOSITE | NIPPON SHOKUBAI CO., LTD. (JP) | 1998-04-21 | — | — | US | disclosed |
| US-5558803-A | ADDITION-CONDENSATION GRAFT COPOLYMERS FOR DIELECTRIC PARTICLES AND INSULATING LIQUIDS | NIPPON SHOKUBAI CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| US-5376294-A | A dielectric particle and a polysiloxane/acrylic ester additive in a dielectric dispersant medium; large shear stress and low current density; stability; nonsettling | NIPPON SHOKUBAI CO., LTD. (JP) | 1994-12-27 | — | — | US | disclosed |