Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 3/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717830 | 1.00 | CNR2 (0.47) | CNR2HTR4OPRL1OPRM1OPRK1 | |
| SCHEMBL8722697 | 0.99 | OPRL1 (0.48) | CNR2HTR4OPRL1OPRM1OPRK1 | |
| SCHEMBL8722696 | 0.99 | OPRL1 (0.48) | CNR2HTR4OPRL1OPRM1OPRK1 | |
| SCHEMBL8718168 | 0.96 | HTR4 (0.51) | CNR2HTR4OPRL1OPRM1OPRK1 | |
| SCHEMBL8718167 | 0.96 | HTR4 (0.51) | CNR2HTR4OPRL1OPRM1OPRK1 | |
| SCHEMBL8720700 | 0.87 | CNR2 (0.50) | CNR2HTR4HTR3AHTR3EHTR3B | |
| SCHEMBL8720701 | 0.87 | CNR2 (0.50) | CNR2HTR4HTR3AHTR3EHTR3B | |
| SCHEMBL8718160 | 0.84 | L3MBTL1 (0.60) | OPRK1HTR3AADORA2A | |
| SCHEMBL8718161 | 0.84 | L3MBTL1 (0.60) | OPRK1HTR3AADORA2A | |
| SCHEMBL8688595 | 0.83 | HTR3A (0.63) | CNR2HTR3AHTR3EHTR3BHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712408-B1 | TROPYL 7-AZAINDOL-3-YLCARBOXYAMIDES AS ANTITUSSIVE AGENT | DOMPE SPA (IT) | 1998-10-28 | — | — | EP | disclosed |