Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8719002 | 0.85 | L3MBTL1 (0.37) | L3MBTL1ALDH1A1TSHROPRM1MAPK1 | |
| SCHEMBL8718189 | 0.81 | ALDH1A1 (0.39) | L3MBTL1ALDH1A1TSHRMAPK1ATM | |
| SCHEMBL8718165 | 0.77 | LMNA (0.40) | L3MBTL1ALDH1A1TSHRMAPK1ATM | |
| SCHEMBL3977324 | 0.72 | CRBN (0.42) | L3MBTL1ALDH1A1SMN1; SMN2KMT2APOLB | |
| SCHEMBL8715545 | 0.72 | PDE4A (0.39) | L3MBTL1ALDH1A1TSHROPRM1MAPK1 | |
| SCHEMBL1099201 | 0.71 | HTR2C (0.46) | L3MBTL1ALDH1A1TSHROPRM1KMT2A | |
| SCHEMBL6588410 | 0.69 | CYP2D6 (0.46) | L3MBTL1ALDH1A1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL7697475 | 0.69 | ALDH1A1 (0.53) | L3MBTL1ALDH1A1TSHRSMN1; SMN2KMT2A | |
| SCHEMBL3973868 | 0.69 | HTR2A (0.47) | L3MBTL1ALDH1A1TSHRSMN1; SMN2KMT2A | |
| SCHEMBL3977717 | 0.68 | ALDH1A1 (0.39) | L3MBTL1ALDH1A1TSHROPRM1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739132-A | ENDOTHOXIN SHOCK; NEPHRITIS | TANABE SEIYAKU CO., LTD. (JP) | 1998-04-14 | — | — | US | disclosed |
| EP-0579059-A1 | Pyridazinone derivatives and processes for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1994-01-19 | — | — | EP | disclosed |