Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR1 | P25024 | 8/20 | 0.55 |
| ▸ | CXCR2 | P25025 | 8/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.42 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.42 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8712603 | 0.88 | NPC1 (0.48) | CXCR1CXCR2NPC1RAB9AMAPT | |
| SCHEMBL8904630 | 0.85 | CXCR1 (0.50) | CXCR1CXCR2NPC1RAB9AMAPT | |
| SCHEMBL8712543 | 0.78 | MAPT (0.45) | NPC1RAB9AMAPTSMN1; SMN2TSHR | |
| SCHEMBL8718388 | 0.76 | ALDH1A1 (0.48) | NPC1RAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL8718100 | 0.76 | TPSAB1 (0.66) | NPC1RAB9AMAPTSMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL8712518 | 0.74 | F10 (0.42) | MAPTSMN1; SMN2HSD17B10TPSAB1TPSD1 | |
| SCHEMBL5846287 | 0.71 | CXCR1 (1.00) | CXCR1CXCR2ALDH1A1 | |
| SCHEMBL8904101 | 0.71 | RAB9A (0.42) | NPC1RAB9AMAPTSMN1; SMN2KMT2A | |
| SCHEMBL8712746 | 0.71 | RAB9A (0.42) | NPC1RAB9AMAPTSMN1; SMN2KMT2A | |
| SCHEMBL8712984 | 0.70 | MAPT (0.44) | NPC1RAB9AMAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753670-A | ANTICOAGULANTS | THE GREEN CROSS CORPORATION (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5635527-A | ANTAGONIST OF PLATELET MEMBRANE GLYCOPROTEIN; TREATMENT OF THROMBOTIC DISEASES | THE GREEN CROSS CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0712844-A1 | NOVEL FUSED-RING CARBOXYLIC ACID COMPOUND OR SALT THEREOF, AND MEDICINAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-22 | — | — | EP | disclosed |