Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 3/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043463 | 0.70 | FBP1 (0.47) | FBP1PDK1 | |
| SCHEMBL8709996 | 0.69 | HDAC6 (0.37) | GAA | |
| SCHEMBL1250423 | 0.67 | KDM4E (0.42) | GAA | |
| SCHEMBL12615990 | 0.64 | ALDH1A1 (0.38) | GAA | |
| SCHEMBL28177930 | 0.64 | FBP1 (0.59) | FBP1PDK1MGAMGAASI | |
| SCHEMBL909645 | 0.63 | METAP1 (0.41) | FBP1PDK1 | |
| SCHEMBL8054533 | 0.63 | FBP1 (0.50) | FBP1PDK1MGAMGAASI | |
| SCHEMBL8712510 | 0.63 | FBP1 (0.40) | FBP1PDK1 | |
| SCHEMBL1496446 | 0.62 | PDPK1 (0.49) | — | |
| SCHEMBL11833685 | 0.62 | FBP1 (0.67) | FBP1PDK1MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998027092-A1 | THIAZOLE COMPOUNDS AND METHODS OF MODULATING SIGNAL TRANSDUCTION | SUGEN, INC. (US) | 1998-06-25 | — | — | WO | disclosed |