Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.30 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.30 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8719192 | 0.78 | ESR1 (0.30) | — | |
| SCHEMBL8720962 | 0.72 | BCHE (0.35) | ELANEBCHETRPC3TRPC4TRPC5 | |
| SCHEMBL8716298 | 0.70 | MMP3 (0.31) | SMN1; SMN2MMP3 | |
| SCHEMBL8477302 | 0.69 | HCAR3 (0.31) | — | |
| SCHEMBL8716380 | 0.68 | TLR8 (0.34) | SMN1; SMN2ELANEBCHETRPC3TRPC4 | |
| SCHEMBL8715828 | 0.61 | MAPT (0.30) | — | |
| SCHEMBL8716334 | 0.58 | LIMK1 (0.31) | ELANE | |
| SCHEMBL23133067 | 0.55 | SMN1; SMN2 (0.35) | SMN1; SMN2ELANE | |
| SCHEMBL12571300 | 0.54 | TSHR (0.59) | SMN1; SMN2 | |
| SCHEMBL24846527 | 0.54 | HCAR3 (0.37) | SMN1; SMN2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876379-A1 | FUSED 1,2,4-THIADIAZINE AND FUSED 1,4-THIAZINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997026265-A1 | FUSED 1,2,4-THIADIAZINE AND FUSED 1,4-THIAZINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1997-07-24 | — | — | WO | disclosed |