Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716298 | 0.92 | MMP3 (0.31) | — | |
| SCHEMBL8715796 | 0.82 | ESR1 (0.36) | — | |
| SCHEMBL8477373 | 0.71 | ABCC8 (0.41) | — | |
| SCHEMBL7069990 | 0.69 | ADRA2A (0.36) | MAPT | |
| SCHEMBL7492873 | 0.65 | — | — | |
| SCHEMBL8475714 | 0.64 | ABCC8 (0.40) | — | |
| SCHEMBL7570919 | 0.63 | ABCC8 (0.32) | — | |
| SCHEMBL7492919 | 0.63 | ADRA2A (0.31) | MAPT | |
| SCHEMBL8716334 | 0.63 | LIMK1 (0.31) | — | |
| SCHEMBL7065748 | 0.61 | KDM4E (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876379-A1 | FUSED 1,2,4-THIADIAZINE AND FUSED 1,4-THIAZINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997026265-A1 | FUSED 1,2,4-THIADIAZINE AND FUSED 1,4-THIAZINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1997-07-24 | — | — | WO | disclosed |