Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8032745 | 0.81 | MEN1 (0.45) | KMT2ACYP3A4TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL8709945 | 0.80 | ALDH1A1 (0.52) | TP53KMT2ACYP3A4CYP2C19CNR2 | |
| SCHEMBL8041924 | 0.79 | TSHR (0.66) | KMT2ACYP3A4CYP2C19TSHRSMN1; SMN2 | |
| SCHEMBL8047690 | 0.79 | SMN1; SMN2 (0.50) | TP53KMT2ATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL8033699 | 0.78 | KMT2A (0.55) | TP53KMT2ACYP3A4CYP2C19CNR2 | |
| SCHEMBL8712945 | 0.78 | TP53 (0.51) | TP53KMT2ACYP3A4CYP2C19CNR2 | |
| SCHEMBL8710522 | 0.77 | TP53 (0.46) | TP53KMT2ACYP3A4CYP2C19CNR2 | |
| SCHEMBL8042081 | 0.76 | TSHR (0.44) | KMT2ACYP3A4CYP2C19TSHRSMN1; SMN2 | |
| SCHEMBL8046022 | 0.76 | TP53 (0.45) | TP53KMT2ACYP3A4CYP2C19CNR2 | |
| SCHEMBL8716316 | 0.76 | TP53 (0.54) | TP53KMT2ACYP3A4CYP2C19CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998027092-A1 | THIAZOLE COMPOUNDS AND METHODS OF MODULATING SIGNAL TRANSDUCTION | SUGEN, INC. (US) | 1998-06-25 | — | — | WO | disclosed |