Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.36 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716801 | 0.76 | NPC1 (0.47) | ALDH1A1SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL8719479 | 0.76 | ALOX15 (0.42) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL535646 | 0.72 | ALDH1A1 (0.73) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL31401930 | 0.72 | ALDH1A1 (0.73) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL20818485 | 0.72 | ALDH1A1 (0.50) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL29922833 | 0.72 | ALDH1A1 (0.50) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL181586 | 0.72 | ALDH1A1 (0.50) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| Fluoride SCHEMBL27600467 | 0.71 | ALDH1A1 (0.70) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL28713393 | 0.71 | ALDH1A1 (0.70) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| Benzene SCHEMBL28241676 | 0.71 | ALDH1A1 (0.70) | ALDH1A1HPGDHTTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756525-A | USING A THIAZOLIDINEDIONE COMPOUND | BEECHAM GROUP PLC (GB) | 1998-05-26 | — | — | US | disclosed |