SCHEMBL8719741

SCHEMBL8719741

CC(NC(=O)OCc1ccccc1)C(=O)Oc1ccc(NC(=O)c2cc3cc(C(=N)N)ccc3o2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.47
MAPT P10636 3/20 0.47
TP53 P04637 3/20 0.47
PLAU P00749 6/20 0.47
NPC1 O15118 5/20 0.45
RAB9A P51151 5/20 0.45
TSHR P16473 2/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
HSD17B10 Q99714 2/20 0.45
MAPK1 P28482 1/20 0.45
CASP3 P42574 1/20 0.45
SENP7 Q9BQF6 1/20 0.45
SENP6 Q9GZR1 1/20 0.45
ALPG P10696 1/20 0.44
F2 P00734 5/20 0.44
PLG P00747 5/20 0.44
PLAT P00750 5/20 0.44
KLK8 O60259 2/20 0.44
F10 P00742 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8903947 0.83 F2 (0.49) SMN1; SMN2MAPTTP53PLAUNPC1
SCHEMBL8718226 0.82 SMN1; SMN2 (0.52) SMN1; SMN2MAPTTP53PLAUNPC1
SCHEMBL8713127 0.81 MAPT (0.47) SMN1; SMN2MAPTTP53PLAUNPC1
SCHEMBL8718070 0.78 SMN1; SMN2 (0.44) SMN1; SMN2MAPTTP53PLAUNPC1
SCHEMBL8716564 0.78 ITGB3 (0.56) SMN1; SMN2MAPTTP53PLAUNPC1
SCHEMBL8718457 0.78 PLG (0.55) SMN1; SMN2MAPTTP53PLAUNPC1
SCHEMBL8717795 0.75 F2 (0.57) SMN1; SMN2TP53PLAUNPC1RAB9A
SCHEMBL8718100 0.73 TPSAB1 (0.66) SMN1; SMN2MAPTTP53PLAUNPC1
SCHEMBL1286216 0.72 ELANE (0.59) NPC1RAB9AMEN1KMT2A
SCHEMBL8903290 0.72 HDAC8 (0.47) SMN1; SMN2MAPTTP53NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5753670-A ANTICOAGULANTS THE GREEN CROSS CORPORATION (JP) 1998-05-19 US disclosed