Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 9/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.38 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720343 | 0.86 | DPP4 (0.45) | OPRM1 | |
| SCHEMBL8717426 | 0.81 | DPP4 (0.40) | LMNAOPRM1 | |
| SCHEMBL8717613 | 0.81 | DPP4 (0.35) | — | |
| SCHEMBL8716987 | 0.81 | GRIN2B (0.43) | LMNAALDH1A1CYP2D6RAB9A | |
| SCHEMBL8717605 | 0.80 | DPP4 (0.46) | MEN1KMT2A | |
| SCHEMBL8719795 | 0.80 | DPP7 (0.43) | OPRM1 | |
| SCHEMBL6425485 | 0.80 | KCNA3 (0.44) | OPRM1CYP2D6 | |
| SCHEMBL8717438 | 0.77 | DPP4 (0.48) | — | |
| SCHEMBL8719817 | 0.73 | ADRA2A (0.42) | OPRM1ALDH1A1HTTMEN1CYP2D6 | |
| SCHEMBL8719914 | 0.72 | CHRM2 (0.40) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569802-B1 | Arylacetamides | MERCK PATENT GMBH (DE) | 1998-07-15 | — | — | EP | disclosed |
| EP-0569802-A1 | Arylacetamides | MERCK PATENT GmbH (DE) | 1993-11-18 | — | — | EP | disclosed |