Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 7/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7659205 | 0.86 | GHSR (0.43) | GHSRCTSBCTSSCTSKMMP9 | |
| SCHEMBL6317705 | 0.85 | GHSR (0.48) | GHSRCTSBCTSSCTSKMMP9 | |
| SCHEMBL7286769 | 0.84 | CTSB (0.49) | GHSRCTSBCTSSCTSKMMP9 | |
| SCHEMBL1401196 | 0.84 | CTSB (0.49) | GHSRCTSBCTSSCTSKMMP9 | |
| SCHEMBL3266674 | 0.84 | CTSB (0.49) | GHSRCTSBCTSSCTSKMMP9 | |
| SCHEMBL29624575 | 0.84 | CTSB (0.49) | GHSRCTSBCTSSCTSKMMP9 | |
| SCHEMBL31407327 | 0.84 | CTSB (0.49) | GHSRCTSBCTSSCTSKMMP9 | |
| SCHEMBL7659094 | 0.84 | GHSR (0.42) | GHSRCTSBCTSSCTSKMMP9 | |
| SCHEMBL3266843 | 0.83 | GHSR (0.47) | GHSRCTSBCTSSCTSKMMP9 | |
| SCHEMBL6318655 | 0.83 | GHSR (0.44) | GHSRCTSBCTSSCTSKMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833845-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1998-04-08 | — | — | EP | disclosed |
| WO-1997000894-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-01-09 | — | — | WO | disclosed |