Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL676411 | 0.93 | TSHR (0.45) | TSHRALDH1A1THRB | |
| SCHEMBL547837 | 0.92 | ALDH1A1 (0.39) | TSHRALDH1A1THRB | |
| Hydrochloric Acid SCHEMBL248062 | 0.91 | TSHR (0.44) | TSHRALDH1A1THRB | |
| SCHEMBL1194149 | 0.76 | ALDH1A1 (0.37) | TSHRALDH1A1THRB | |
| Sulfuric Acid SCHEMBL28523964 | 0.76 | THRB (0.50) | TSHRALDH1A1THRB | |
| SCHEMBL14994268 | 0.76 | TSHR (0.44) | TSHRALDH1A1THRB | |
| Sulfuric Acid SCHEMBL8717714 | 0.75 | ALDH1A1 (0.47) | TSHRALDH1A1THRB | |
| Sulfuric Acid SCHEMBL1683726 | 0.74 | THRB (0.63) | TSHRALDH1A1THRB | |
| SCHEMBL10495130 | 0.74 | THRB (0.48) | TSHRALDH1A1THRB | |
| SCHEMBL8579619 | 0.74 | THRB (0.44) | TSHRALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5783533-A | COPOLYMER CONTAINING ACRYLIC ACID TYPE GROUPS, ACRYLIC, VINYL, OR ALLYL MONOMERS WITH PENDANT AMMONIUM OR SULFONIUM GROUPS, POSSIBLY WITH POLYOXYALKYLENE ETHER SECTION, RHEOLOGY MODIFIERS | COATEX S.A. (FR) | 1998-07-21 | — | — | US | claimed |
| CN-110431172-B | Method for producing carboxyl group-containing nitrile rubber | 日本瑞翁株式会社 | 2022-03-25 | — | — | CN | disclosed |
| US-5783533-A | COPOLYMER CONTAINING ACRYLIC ACID TYPE GROUPS, ACRYLIC, VINYL, OR ALLYL MONOMERS WITH PENDANT AMMONIUM OR SULFONIUM GROUPS, POSSIBLY WITH POLYOXYALKYLENE ETHER SECTION, RHEOLOGY MODIFIERS | COATEX S.A. (FR) | 1998-07-21 | — | — | US | disclosed |