Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 2/20 | 0.32 |
| ▸ | FNTB | P49356 | 2/20 | 0.32 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL930347 | 0.85 | PTGS1 (0.45) | PTGS1GSTK1ACEKDM4EMAPT | |
| SCHEMBL929577 | 0.82 | PTGS1 (0.43) | PTGS1GSTK1ACEKDM4EMAPT | |
| SCHEMBL7594016 | 0.81 | PTGS1 (0.64) | PTGS1GSTK1ACEKDM4EMAPT | |
| SCHEMBL7594008 | 0.81 | PTGS1 (0.64) | PTGS1GSTK1ACEKDM4EMAPT | |
| SCHEMBL929445 | 0.79 | PTGS1 (0.41) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL929533 | 0.78 | PTGS1 (0.40) | PTGS1GSTK1FNTAFNTBPGGT1B | |
| SCHEMBL31287971 | 0.78 | PTGS1 (0.54) | PTGS1GSTK1ACEKDM4EMAPT | |
| SCHEMBL30392676 | 0.78 | PTGS1 (0.61) | PTGS1GSTK1ACEKDM4EMAPT | |
| SCHEMBL29567569 | 0.78 | PTGS1 (0.54) | PTGS1GSTK1ACEKDM4EMAPT | |
| SCHEMBL22195345 | 0.78 | BMP1 (0.41) | PTGS1GSTK1ACEKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5759515-A | PEPTIDE IS BOUND TO MEDICALLY USEFUL METAL IONS, DIAGNOSTIC IMAGING, OTHER DIAGNOSTIC AND THERAPEUTIC APPLICATIONS | RHOMED INCORPORATED (US) | 1998-06-02 | — | — | US | disclosed |
| WO-1995001188-A1 | POLYVALENT PEPTIDE PHARMACEUTICAL APPLICATIONS | RHOMED INCORPORATED (US) | 1995-01-12 | — | — | WO | disclosed |