Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2950066 | 0.85 | LMNA (0.40) | SIGMAR1ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL8716789 | 0.85 | POLB (0.49) | CHRM2DRD3ALDH1A1SLC6A4KMT2A | |
| SCHEMBL2950815 | 0.85 | LMNA (0.40) | SIGMAR1ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL9130649 | 0.85 | POLB (0.49) | CHRM2DRD3ALDH1A1SLC6A4KMT2A | |
| SCHEMBL9015341 | 0.85 | UGCG (0.44) | CHRM2DRD3ALDH1A1LMNAKMT2A | |
| SCHEMBL5844785 | 0.84 | ALDH1A1 (0.46) | ALDH1A1LMNAKMT2AMEN1MITF | |
| SCHEMBL5559778 | 0.84 | ALDH1A1 (0.46) | ALDH1A1LMNAKMT2AMEN1MITF | |
| SCHEMBL5559775 | 0.84 | ALDH1A1 (0.46) | ALDH1A1LMNAKMT2AMEN1MITF | |
| SCHEMBL9677137 | 0.83 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1MITFRAB9A | |
| SCHEMBL17574260 | 0.83 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1MITFRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569802-B1 | Arylacetamides | MERCK PATENT GMBH (DE) | 1998-07-15 | — | — | EP | disclosed |
| US-5532266-A | Acrylacetamides | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | disclosed |
| EP-0569802-A1 | Arylacetamides | MERCK PATENT GmbH (DE) | 1993-11-18 | — | — | EP | disclosed |