Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716789 | 1.00 | POLB (0.49) | POLBKDM4EALDH1A1UTS2RUSP2 | |
| SCHEMBL8720321 | 0.85 | HRH3 (0.45) | KDM4EALDH1A1USP2TSHRMEN1 | |
| SCHEMBL2950815 | 0.83 | LMNA (0.40) | POLBKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL2950066 | 0.83 | LMNA (0.40) | POLBKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9015341 | 0.83 | UGCG (0.44) | POLBKDM4EALDH1A1ALOX15SLC6A2 | |
| SCHEMBL5559775 | 0.83 | ALDH1A1 (0.46) | POLBKDM4EALDH1A1TSHRCYP3A4 | |
| SCHEMBL5844785 | 0.83 | ALDH1A1 (0.46) | POLBKDM4EALDH1A1TSHRCYP3A4 | |
| SCHEMBL5559778 | 0.83 | ALDH1A1 (0.46) | POLBKDM4EALDH1A1TSHRCYP3A4 | |
| SCHEMBL14451981 | 0.81 | RPS6KB1 (0.47) | AKT1SLC6A2SLC6A4OPRM1SLC6A3 | |
| SCHEMBL17574260 | 0.81 | ALDH1A1 (0.45) | POLBALDH1A1TSHRNTSR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5472961-A | Acetamides | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-12-05 | — | — | US | disclosed |