Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGCG | Q16739 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720321 | 0.85 | HRH3 (0.45) | ALDH1A1SMN1; SMN2KDM4EKMT2ALMNA | |
| SCHEMBL9512267 | 0.84 | LTA4H (0.40) | KMT2AGPR88CYP3A4CYP2D6LTA4H | |
| SCHEMBL9512275 | 0.84 | LTA4H (0.40) | KMT2AGPR88CYP3A4CYP2D6LTA4H | |
| SCHEMBL8716789 | 0.83 | POLB (0.49) | ALDH1A1HTR1AKDM4EHIF1AKMT2A | |
| SCHEMBL9130649 | 0.83 | POLB (0.49) | ALDH1A1HTR1AKDM4EHIF1AKMT2A | |
| SCHEMBL2950815 | 0.83 | LMNA (0.40) | ALDH1A1TDP1KDM4EKMT2APOLB | |
| SCHEMBL2950066 | 0.83 | LMNA (0.40) | ALDH1A1TDP1KDM4EKMT2APOLB | |
| SCHEMBL5559778 | 0.83 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2KDM4EHIF1AKMT2A | |
| SCHEMBL5844785 | 0.83 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2KDM4EHIF1AKMT2A | |
| SCHEMBL5559775 | 0.83 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2KDM4EHIF1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532266-A | Acrylacetamides | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | disclosed |