Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 4/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717616 | 0.89 | ALDH1A1 (0.37) | ALDH1A1GAAKDM4EXBP1MAPK1 | |
| SCHEMBL8716993 | 0.89 | ALDH1A1 (0.40) | ALDH1A1GAAKDM4EXBP1MAPK1 | |
| SCHEMBL6425483 | 0.87 | KCNA3 (0.44) | ALDH1A1KDM4EOPRK1KCNA3 | |
| SCHEMBL8350936 | 0.85 | ALDH1A1 (0.38) | ALDH1A1GAAKDM4EHRH1CNR2 | |
| SCHEMBL8720345 | 0.85 | OPRK1 (0.42) | CNR2OPRK1 | |
| SCHEMBL8719953 | 0.83 | ALDH1A1 (0.42) | ALDH1A1HRH1SMN1; SMN2 | |
| SCHEMBL14347848 | 0.77 | MEN1 (0.40) | ALDH1A1GAAKDM4EHRH1CNR2 | |
| SCHEMBL8720326 | 0.77 | HRH3 (0.44) | ALDH1A1KDM4EHRH1SMN1; SMN2NPSR1 | |
| SCHEMBL10272308 | 0.72 | ALDH1A1 (0.57) | ALDH1A1HRH1 | |
| SCHEMBL13479261 | 0.72 | ALDH1A1 (0.57) | ALDH1A1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569802-B1 | Arylacetamides | MERCK PATENT GMBH (DE) | 1998-07-15 | — | — | EP | disclosed |
| EP-0569802-A1 | Arylacetamides | MERCK PATENT GmbH (DE) | 1993-11-18 | — | — | EP | disclosed |