Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21765852 | 0.83 | ALDH1A1 (0.43) | TACR1KMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL5883327 | 0.82 | TACR1 (0.54) | TACR1KMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL11963730 | 0.81 | ALDH1A1 (0.50) | TACR1KMT2ASMN1; SMN2MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5883686 | 0.80 | TACR1 (0.52) | TACR1KMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL31393815 | 0.79 | TACR1 (0.51) | TACR1KMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL13041531 | 0.77 | POLB (0.51) | SMN1; SMN2ALDH1A1LTB4R2KDM4EMAPT | |
| SCHEMBL4781144 | 0.77 | CYP3A4 (0.46) | ALDH1A1KDM4EMAPTTSHR | |
| SCHEMBL21765870 | 0.77 | TSPO (0.49) | TACR1KMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL7450697 | 0.76 | TACR1 (0.49) | TACR1KMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL7451450 | 0.76 | TACR1 (0.63) | TACR1KMT2ASMN1; SMN2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827869-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-27 | — | — | US | disclosed |