Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 2/20 | 0.49 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21765852 | 0.92 | ALDH1A1 (0.43) | TSPOALDH1A1MAPTGAATSHR | |
| SCHEMBL4781144 | 0.81 | CYP3A4 (0.46) | ALDH1A1MAPTTSHRTP53LMNA | |
| SCHEMBL21765851 | 0.80 | ALDH1A1 (0.35) | TSPOALDH1A1MAPTGAATSHR | |
| SCHEMBL15224071 | 0.79 | TSPO (0.55) | TSPOFSCN1ALDH1A1MAPTGAA | |
| SCHEMBL13684202 | 0.79 | ALDH1A1 (0.47) | TSPOALDH1A1MAPTGAATSHR | |
| SCHEMBL13041531 | 0.78 | POLB (0.51) | ALDH1A1MAPTGAATSHRTP53 | |
| SCHEMBL6529361 | 0.77 | ESR1 (0.46) | TSPOALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL13007694 | 0.77 | SIGMAR1 (0.61) | ALDH1A1TSHRLMNAKDM4E | |
| SCHEMBL8720338 | 0.77 | TACR1 (0.57) | ALDH1A1MAPTTSHRSMN1; SMN2KDM4E | |
| SCHEMBL5536970 | 0.75 | TSPO (0.55) | TSPOFSCN1ALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020041270-A1 | COLLECTIONS OF PEPTIDES, PEPTIDE AGENTS, AND METHODS OF USE THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2020-02-27 | — | — | WO | disclosed |