SCHEMBL8720344

SCHEMBL8720344

O=P(Oc1cc(Cl)c(Cl)cc1Cl)(Oc1cc(Cl)c(Cl)cc1Cl)Sc1cc(Cl)c(Cl)cc1Cl

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
LMNA P02545 1/20 0.33
NR1I2 O75469 1/20 0.31
ADRA2A P08913 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
TACR2 P21452 1/20 0.31
DRD1 P21728 1/20 0.31
SLC6A2 P23975 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
ADORA1 P30542 1/20 0.31
SLC6A4 P31645 1/20 0.31
OPRM1 P35372 1/20 0.31
DRD3 P35462 1/20 0.31
OPRK1 P41145 1/20 0.31
HTR6 P50406 1/20 0.31
SLC6A3 Q01959 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8755038 0.76 ALDH1A1 (0.39) MEN1KMT2ALMNAALDH1A1
SCHEMBL5823192 0.73 TDP1 (0.44) MEN1KMT2ALMNANR1I2ADORA3
SCHEMBL15315299 0.71 INPPL1 (0.58) LMNAALDH1A1MAPTNPSR1
SCHEMBL11322565 0.69 NR1I2 (0.35) MEN1KMT2ALMNANR1I2ADRA2A
SCHEMBL18406961 0.68 LMNA (0.42) LMNANR1I2ADRA2AADORA3ADRA2B
SCHEMBL15656094 0.68 ALDH1A1 (0.46) MEN1KMT2ALMNANR1I2ADRA2A
SCHEMBL10934119 0.67 TDP1 (0.36) MEN1KMT2ALMNAALDH1A1MAPT
SCHEMBL22477311 0.65 LMNA (0.47) MEN1KMT2ALMNANR1I2ADRA2A
SCHEMBL7773998 0.64 NR1I2 (0.35) LMNANR1I2ADRA2AADORA3ADRA2B
SCHEMBL28856235 0.64 LMNA (0.39) LMNAALDH1A1MAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5762808-A Destruction of electron affinic contaminants during water treatment using free radical processes RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1998-06-09 US claimed