SCHEMBL8755038

SCHEMBL8755038

COP(=O)(OC)Sc1cc(Cl)c(Cl)cc1Cl

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
CYP3A4 P08684 1/20 0.39
TSHR P16473 1/20 0.39
HIF1A Q16665 1/20 0.39
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
LMNA P02545 1/20 0.31
DDB1 Q16531 1/20 0.30
CRBN Q96SW2 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8720344 0.76 MEN1 (0.33) ALDH1A1MEN1KMT2ALMNA
Salicylanilide SCHEMBL1877537 0.74 MEN1 (0.55) MEN1KMT2ALMNA
SCHEMBL11110277 0.72 TDP1 (0.42) ALDH1A1CYP3A4TSHRHIF1AMEN1
SCHEMBL5934309 0.71 MMP2 (0.41) ALDH1A1MEN1KMT2ALMNA
SCHEMBL21078775 0.65 KCNH2 (0.52) ALDH1A1TSHRMEN1KMT2ALMNA
SCHEMBL15362374 0.64 MEN1 (0.44) ALDH1A1CYP3A4TSHRMEN1KMT2A
SCHEMBL21078778 0.64 TSHR (0.40) ALDH1A1CYP3A4TSHRMEN1KMT2A
SCHEMBL7263840 0.63 MEN1 (0.61) ALDH1A1CYP3A4TSHRHIF1AMEN1
SCHEMBL4636283 0.63 MEN1 (0.48) ALDH1A1CYP3A4TSHRMEN1KMT2A
SCHEMBL30050744 0.63 MEN1 (0.48) ALDH1A1CYP3A4TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0449975-B1 NON-TIN-BASED, LOW TOXICITY ANTI-FOULING AGENTS BATTELLE MEMORIAL INSTITUTE (US) 1997-04-23 EP claimed
WO-1990006975-A1 NON-TIN-BASED, LOW TOXICITY ANTI-FOULING AGENTS BATTELLE MEMORIAL INSTITUTE (US) 1990-06-28 WO claimed
US-5441743-A In thermoplastic or thermosetting binder BATTELLE MEMORIAL INSTITUTE (US) 1995-08-15 US disclosed
WO-1990006975-A1 NON-TIN-BASED, LOW TOXICITY ANTI-FOULING AGENTS BATTELLE MEMORIAL INSTITUTE (US) 1990-06-28 WO disclosed