Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.51 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.50 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 4/20 | 0.48 |
| ▸ | DRD2 | P14416 | 3/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8724139 | 0.82 | DRD3 (0.47) | HTR7MEN1KMT2ADRD3DRD2 | |
| SCHEMBL8720703 | 0.79 | ADRA1D (0.55) | SIGMAR1HTR7MEN1KMT2ATP53 | |
| SCHEMBL8724727 | 0.79 | ADRA1D (0.55) | SIGMAR1HTR7MEN1KMT2ATP53 | |
| SCHEMBL16273473 | 0.74 | SIGMAR1 (0.62) | SIGMAR1CARM1PRMT6HTR7MEN1 | |
| SCHEMBL15779804 | 0.72 | DRD2 (0.76) | SIGMAR1CARM1PRMT6MEN1KMT2A | |
| SCHEMBL27571644 | 0.72 | DRD2 (0.76) | SIGMAR1CARM1PRMT6MEN1KMT2A | |
| SCHEMBL8724505 | 0.72 | SLC18A3 (0.52) | CARM1PRMT6DRD3DRD2ADRA1D | |
| SCHEMBL8476000 | 0.71 | CARM1 (0.82) | SIGMAR1CARM1PRMT6MEN1KMT2A | |
| SCHEMBL256656 | 0.71 | DRD2 (0.78) | SIGMAR1CARM1PRMT6MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7259165 | 0.70 | SIGMAR1 (0.75) | SIGMAR1CARM1PRMT6HTR7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998042692-A1 | PIPERAZINES DERIVED FROM CYCLIC AMINES, PREPARATION AND APPLICATION THEREOF AS MEDICINES | PIERRE FABRE MEDICAMENT (FR) | 1998-10-01 | — | — | WO | disclosed |