Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 3/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.55 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | AVPR2 | P30518 | 6/20 | 0.53 |
| ▸ | AVPR1A | P37288 | 6/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720703 | 1.00 | ADRA1D (0.55) | ADRA1DADRA1AADRA1BKDM4EALDH1A1 | |
| SCHEMBL8724505 | 0.92 | SLC18A3 (0.52) | ADRA1DADRA1AADRA1BKDM4EALDH1A1 | |
| SCHEMBL8720267 | 0.83 | AVPR2 (0.58) | KDM4EALDH1A1TDP1AVPR2AVPR1A | |
| SCHEMBL8722874 | 0.83 | AVPR2 (0.58) | KDM4EALDH1A1TDP1AVPR2AVPR1A | |
| SCHEMBL8719681 | 0.82 | ALDH1A1 (0.72) | ADRA1AKDM4EALDH1A1TDP1DRD3 | |
| SCHEMBL8720336 | 0.82 | ALDH1A1 (0.72) | ADRA1AKDM4EALDH1A1TDP1DRD3 | |
| SCHEMBL8719445 | 0.82 | ALDH1A1 (0.72) | ADRA1AKDM4EALDH1A1TDP1DRD3 | |
| SCHEMBL8724501 | 0.82 | ALDH1A1 (0.72) | ADRA1AKDM4EALDH1A1TDP1DRD3 | |
| SCHEMBL8720341 | 0.81 | ADRA1D (0.65) | ADRA1DADRA1AADRA1BKDM4EALDH1A1 | |
| SCHEMBL8720449 | 0.79 | SIGMAR1 (0.51) | ADRA1DADRA1AADRA1BSIGMAR1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998042692-A1 | PIPERAZINES DERIVED FROM CYCLIC AMINES, PREPARATION AND APPLICATION THEREOF AS MEDICINES | PIERRE FABRE MEDICAMENT (FR) | 1998-10-01 | — | — | WO | disclosed |