Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RB1 | P06400 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.34 |
| ▸ | BRD4 | O60885 | 3/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | CCKAR | P32238 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 3/20 | 0.32 |
| ▸ | CTSK | P43235 | 3/20 | 0.32 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717910 | 0.92 | SMN1; SMN2 (0.38) | SMN1; SMN2RB1PKMTBXA2RPTGDR | |
| SCHEMBL8715076 | 0.87 | BRD4 (0.34) | SMN1; SMN2PKMBRD4CYP2C9ALDH1A1 | |
| SCHEMBL9414927 | 0.78 | PNMT (0.40) | SMN1; SMN2RB1PKMTBXA2RPSEN1 | |
| SCHEMBL9414815 | 0.77 | SMN1; SMN2 (0.38) | SMN1; SMN2RB1TBXA2RPSEN1PSEN2 | |
| SCHEMBL8714966 | 0.75 | MTNR1A (0.33) | SMN1; SMN2ALDH1A1KCNH2 | |
| SCHEMBL9414693 | 0.74 | SMN1; SMN2 (0.36) | SMN1; SMN2KCNH2 | |
| Iodide SCHEMBL8720179 | 0.73 | SMN1; SMN2 (0.35) | SMN1; SMN2KCNH2 | |
| SCHEMBL8110725 | 0.70 | SMN1; SMN2 (0.48) | SMN1; SMN2 | |
| SCHEMBL8718071 | 0.67 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1KCNH2 | |
| SCHEMBL8717945 | 0.67 | PDE4B (0.33) | SMN1; SMN2PKMCYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739132-A | ENDOTHOXIN SHOCK; NEPHRITIS | TANABE SEIYAKU CO., LTD. (JP) | 1998-04-14 | — | — | US | disclosed |