Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | TMPRSS15 | P98073 | 7/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8722086 | 0.91 | CA2 (0.42) | PYGLCA2CA1TMPRSS15PRSS1 | |
| SCHEMBL7715738 | 0.88 | CA1 (0.44) | CA2CA1UTS2RCA12CA9 | |
| SCHEMBL8726548 | 0.82 | ALDH1A1 (0.43) | PYGLCA2CA1UTS2RCA12 | |
| SCHEMBL8722082 | 0.82 | CA1 (0.42) | PYGLCA2CA1CA12CA9 | |
| SCHEMBL8722067 | 0.81 | CA1 (0.47) | CA2CA1CA12CA9ALDH1A1 | |
| SCHEMBL8726191 | 0.81 | CA2 (0.41) | CA2CA1CA12CA9MMP2 | |
| SCHEMBL8726467 | 0.80 | CA2 (0.41) | PYGLCA2CA1CA12CA9 | |
| SCHEMBL7717390 | 0.80 | MAPT (0.36) | CA1UTS2RCA12CA9ALDH1A1 | |
| SCHEMBL8722150 | 0.79 | CA2 (0.42) | PYGLCA2UTS2RALDH1A1LMNA | |
| SCHEMBL8726202 | 0.78 | CA2 (0.46) | CA2CA1UTS2RCA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998035982-A1 | COMPOUNDS FOR USE IN ADEPT | ZENECA LIMITED (GB) | 1998-08-20 | — | — | WO | disclosed |