Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 6/20 | 0.42 |
| ▸ | CA1 | P00915 | 6/20 | 0.42 |
| ▸ | CA9 | Q16790 | 6/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.39 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | GPR132 | Q9UNW8 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8722067 | 0.92 | CA1 (0.47) | ALDH1A1LMNASMN1; SMN2CA12CA1 | |
| SCHEMBL8727972 | 0.88 | ALDH1A1 (0.43) | ALDH1A1LMNASMN1; SMN2CA12CA1 | |
| SCHEMBL7715738 | 0.86 | CA1 (0.44) | ALDH1A1LMNASMN1; SMN2CA12CA1 | |
| SCHEMBL8722086 | 0.85 | CA2 (0.42) | CA12CA1CA9CA2PYGL | |
| SCHEMBL8722082 | 0.84 | CA1 (0.42) | ALDH1A1CA12CA1CA9CA2 | |
| SCHEMBL8722150 | 0.83 | CA2 (0.42) | ALDH1A1LMNASMN1; SMN2CA2UTS2R | |
| SCHEMBL8726467 | 0.82 | CA2 (0.41) | CA12CA1CA9CA2PYGL | |
| SCHEMBL8722107 | 0.82 | PYGL (0.36) | ALDH1A1LMNASMN1; SMN2CA12CA1 | |
| SCHEMBL7711928 | 0.80 | MCL1 (0.43) | CA1CA2 | |
| SCHEMBL7717390 | 0.78 | MAPT (0.36) | ALDH1A1LMNASMN1; SMN2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998035982-A1 | COMPOUNDS FOR USE IN ADEPT | ZENECA LIMITED (GB) | 1998-08-20 | — | — | WO | disclosed |