Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.37 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | ESRRA | P11474 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8726450 | 0.85 | ALDH1A1 (0.39) | NPSR1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8726211 | 0.79 | NPSR1 (0.37) | NPSR1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8726177 | 0.78 | ALDH1A1 (0.37) | NPSR1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6778559 | 0.75 | MAPT (0.53) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL8726250 | 0.75 | ALDH1A1 (0.35) | NPSR1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL27453160 | 0.74 | MAPT (0.54) | NPSR1ALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL29024480 | 0.71 | CTSB (0.54) | NPSR1ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2644918 | 0.70 | MAPT (0.44) | NPSR1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL24834183 | 0.69 | MAPT (0.50) | NPSR1ALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL30571505 | 0.69 | ALDH1A1 (0.50) | NPSR1ALDH1A1HPGDSMN1; SMN2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998035982-A1 | COMPOUNDS FOR USE IN ADEPT | ZENECA LIMITED (GB) | 1998-08-20 | — | — | WO | disclosed |