Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | MMP12 | P39900 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8726177 | 0.92 | ALDH1A1 (0.37) | NPSR1ALDH1A1POLBMAPTMEN1 | |
| SCHEMBL8726250 | 0.88 | ALDH1A1 (0.35) | NPSR1ALDH1A1POLBMAPTMEN1 | |
| SCHEMBL8726450 | 0.81 | ALDH1A1 (0.39) | NPSR1ALDH1A1POLBMAPTMEN1 | |
| SCHEMBL8724221 | 0.79 | CA1 (0.42) | ALDH1A1MMP2MMP9MMP12UTS2R | |
| SCHEMBL8722134 | 0.79 | NPSR1 (0.44) | NPSR1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8724211 | 0.75 | MAPT (0.41) | NPSR1ALDH1A1POLBMAPTMEN1 | |
| SCHEMBL8722997 | 0.74 | MAPT (0.37) | ALDH1A1MAPT | |
| SCHEMBL7717390 | 0.74 | MAPT (0.36) | NPSR1ALDH1A1POLBMAPTTDP1 | |
| SCHEMBL8726452 | 0.72 | MAPT (0.40) | NPSR1ALDH1A1POLBMAPTTDP1 | |
| SCHEMBL8722158 | 0.71 | CA2 (0.41) | MMP2MMP9MMP12TDP1UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998035982-A1 | COMPOUNDS FOR USE IN ADEPT | ZENECA LIMITED (GB) | 1998-08-20 | — | — | WO | disclosed |