Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | CD38 | P28907 | 2/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | ADH5 | P11766 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8721485 | 0.89 | NOTUM (0.47) | IDO1NOTUMCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8724176 | 0.87 | CYP1A2 (0.38) | IDO1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8720881 | 0.76 | MEN1 (0.47) | IDO1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8726103 | 0.74 | MEN1 (0.49) | IDO1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8720884 | 0.73 | IDO1 (0.42) | IDO1NOTUMKMT2ACNR1CNR2 | |
| SCHEMBL8724299 | 0.72 | IDO1 (0.49) | IDO1NOTUMCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8721417 | 0.68 | CYP11B1 (0.42) | IDO1NOTUMSMN1; SMN2CNR1CNR2 | |
| SCHEMBL20146977 | 0.67 | SNCA (0.46) | MEN1KMT2A | |
| 1,4-Dichlorobenzene SCHEMBL27827868 | 0.67 | NOTUM (0.82) | IDO1NOTUMCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8331555 | 0.66 | CYP3A4 (0.43) | IDO1CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998000430-A1 | IMIDAZOL DERIVATIVES USEFUL AS NITROGEN MONOXIDE SYNTHASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-08 | — | — | WO | disclosed |