Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.46 |
| ▸ | IDO1 | P14902 | 3/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8724176 | 0.85 | CYP1A2 (0.38) | MEN1KMT2ATSHRALOX15CYP3A4 | |
| SCHEMBL8720881 | 0.84 | MEN1 (0.47) | MEN1KMT2ATSHRALOX15LMNA | |
| SCHEMBL8726099 | 0.82 | PKM (0.41) | MEN1KMT2ALMNACYP3A4CYP1A2 | |
| SCHEMBL8722319 | 0.78 | MEN1 (0.42) | MEN1KMT2ATSHRALOX15LMNA | |
| SCHEMBL8722249 | 0.74 | IDO1 (0.39) | MEN1KMT2ACYP3A4IDO1CYP11B1 | |
| SCHEMBL8724299 | 0.73 | IDO1 (0.49) | MEN1KMT2ACYP3A4IDO1CYP1A2 | |
| SCHEMBL27958208 | 0.73 | CYP11B1 (0.54) | MEN1KMT2ATSHRALOX15LMNA | |
| SCHEMBL27947676 | 0.70 | MEN1 (0.58) | MEN1KMT2ATSHRALOX15LMNA | |
| SCHEMBL29852234 | 0.70 | MEN1 (0.58) | MEN1KMT2ATSHRALOX15LMNA | |
| SCHEMBL16382293 | 0.70 | IDO1 (0.73) | MEN1KMT2ATSHRALOX15LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998000430-A1 | IMIDAZOL DERIVATIVES USEFUL AS NITROGEN MONOXIDE SYNTHASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-08 | — | — | WO | disclosed |