Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | ADH5 | P11766 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720884 | 0.86 | IDO1 (0.42) | IDO1CNR1CNR2NOTUMADH5 | |
| SCHEMBL6334824 | 0.75 | IDO1 (0.65) | IDO1CNR1CNR2NOTUMMEN1 | |
| SCHEMBL8726103 | 0.73 | MEN1 (0.49) | IDO1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL27559817 | 0.73 | IDO1 (0.55) | IDO1CNR1CNR2NOTUMADH5 | |
| SCHEMBL5099510 | 0.72 | CNR1 (0.51) | IDO1CNR1CNR2NOTUMADH5 | |
| SCHEMBL29367195 | 0.72 | IDO1 (0.50) | IDO1CNR1CNR2NOTUMMEN1 | |
| SCHEMBL6342180 | 0.72 | IDO1 (0.70) | IDO1NOTUMMEN1KMT2ACYP1A2 | |
| SCHEMBL8722249 | 0.72 | IDO1 (0.39) | IDO1CNR1CNR2NOTUMADH5 | |
| SCHEMBL8724176 | 0.71 | CYP1A2 (0.38) | IDO1ADH5MEN1KMT2ACYP1A2 | |
| SCHEMBL20512346 | 0.71 | IDO1 (0.49) | IDO1CNR1CNR2NOTUMADH5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998000430-A1 | IMIDAZOL DERIVATIVES USEFUL AS NITROGEN MONOXIDE SYNTHASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-08 | — | — | WO | disclosed |