Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | BCL3 | P20749 | 2/20 | 0.58 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7527740 | 0.82 | KMT2A (0.66) | MEN1KMT2ABCL3CD274HPGD | |
| SCHEMBL31298077 | 0.80 | KMT2A (0.67) | MEN1KMT2ABCL3CD274HPGD | |
| SCHEMBL9760978 | 0.80 | CD274 (0.64) | MEN1KMT2ACD274ALDH1A1HTR1A | |
| SCHEMBL9064849 | 0.80 | HTR4 (0.55) | MEN1KMT2AHPGD | |
| SCHEMBL31518356 | 0.80 | KMT2A (0.63) | MEN1KMT2ABCL3HPGDALDH1A1 | |
| SCHEMBL28602004 | 0.80 | POLB (0.60) | MEN1KMT2ABCL3 | |
| SCHEMBL5795351 | 0.80 | KMT2A (0.63) | MEN1KMT2ABCL3HPGDALDH1A1 | |
| SCHEMBL13164059 | 0.79 | MEN1 (0.66) | MEN1KMT2ABCL3CD274HPGD | |
| SCHEMBL8161181 | 0.79 | BCL3 (0.84) | MEN1KMT2ABCL3CD274HPGD | |
| SCHEMBL21347706 | 0.79 | KMT2A (0.66) | MEN1KMT2ABCL3CD274HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993005088-A1 | CATALYSTS WHICH STABILIZE HYDROHALOCARBON BLOWING AGENT IN POLYURETHANE FOAM FORMULATIONS | ALLIED-SIGNAL INC. (US) | 1993-03-18 | — | — | WO | claimed |
| US-4937306-A | For polyurethanes | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1990-06-26 | — | — | US | claimed |
| EP-0300366-A1 | Non-fugitive aromatic diamine catalytic chain extenders | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1989-01-25 | — | — | EP | claimed |
| US-5840779-A | COMPOSITION COMPRISING POLYISOCYANATE, POLYOL, HYDROFLUOROCARBON BLOWING AGENT, SURFACTANT, POLYAMINE CATALYST; DECREASED DECOMPOSITION OF BLOWING AGENT | ALLIEDSIGNAL INC. (US) | 1998-11-24 | — | — | US | disclosed |
| US-5688834-A | STABLE POLYURETHANE FOAMS | ALLIEDSIGNAL, INC. (US) | 1997-11-18 | — | — | US | disclosed |
| WO-1993005088-A1 | CATALYSTS WHICH STABILIZE HYDROHALOCARBON BLOWING AGENT IN POLYURETHANE FOAM FORMULATIONS | ALLIED-SIGNAL INC. (US) | 1993-03-18 | — | — | WO | disclosed |
| US-5034426-A | Reaction of polyisocyanate, polyol and a chain extender which is also a catalyst because of a tert-amine side chain | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1991-07-23 | — | — | US | disclosed |
| US-4937306-A | For polyurethanes | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1990-06-26 | — | — | US | disclosed |
| EP-0300366-A1 | Non-fugitive aromatic diamine catalytic chain extenders | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1989-01-25 | — | — | EP | disclosed |